Skip to main content

Science & Tech

By mapping the gut ecosystem with rigorous science and proprietary technology, we’re unlocking a future of better care.

Clinical-grade demands superior science and technology

At Microba, we pair rigorous science with precision technology to deliver insights you can trust. Every step, from sample collection to report generation, is designed for accuracy, completeness, and clinical relevance.

We choose the hard road of building new scientific and technological standards because that is what’s needed to change the future of healthcare. Our integrated approach delivers a more accurate picture of the gut microbiome and its role in health, helping practitioners make evidence-based decisions with confidence.

Our Science

For nearly a decade, Microba has led gut microbiome science, driving discoveries that shape understanding and enable confident, clinical-grade care.

Our multidisciplinary team of scientists, researchers, doctors and practitioners spans the fields of microbiology, gastroenterology, immunology, infectious disease, bioinformatics, metagenomic sequencing and clinical translation. Together, our team has produced hundreds of publications and received thousands of citations in peer-reviewed scientific journals.

Through ongoing research, including the Microba Science Review – draws on more than 1500+ peer-reviewed studies and over 7500+ hours of evaluation – we continue to raise the standard for gut microbiome testing.

Our Technology

Microba’s technology delivers comprehensive gut microbiome profiling using next-generation metagenomic sequencing – the gold standard in gut microbiome research.

From the Microba Smart Stool Sampling kit to our pathology-grade ISO15189-accredited laboratories and ISO15189 and ISO13485-accredited bioinformatics, every step of our process is designed for precision, reproducibility and scientific integrity. This commitment to excellence defines what clinical-grade microbiome testing should be, and sets a new standard for care.

Do you know exactly which oral species Microbiome Explorer can identify?

Yes — any species whose primary site of colonisation is the mouth will be flagged. We use the Human Oral Microbiome Database, or HOMD, to identify these species. If they're detected in the stool sample, they're listed in the Microbiome Explorer report as oral species.

How many Archaea species can Microbiome Explorer identify?

Microbiome Explorer can identify approximately 240 Archaea species, including methane producers such as Methanobrevibacter smithii.

How many protist species can Microbiome Explorer identify?

The Microbiome Explorer range can identify around 425 protist species. That includes Blastocystis hominis and seven Blastocystis subtypes, which you'll find in the Protists section of Species Explorer.

Microbiome Explorer Comprehensive also detects five protist species and genera using a CE-certified RT-PCR test.

What's the difference between shotgun metagenomic sequencing and culture-based methods?

They're two very different approaches, and they answer different questions.

Shotgun metagenomic sequencing reads all the DNA in a sample. That means we can identify microbes down to species — and sometimes strain — level, and see their functional genes and pathways. It tells us both who's there and what they can do. It detects bacteria, fungi, protists, and Archaea, and can even discover entirely new species.

Culture-based methods grow live organisms in nutrient media. They're useful for confirming specific organisms with known growth requirements — pathogens, Bifidobacterium, Lactobacillus — and for testing antimicrobial susceptibility. But culture only captures a small subset of the microbiome. Current research suggests we only know the culture conditions for about 63% of gut microbes, and testing even that portion would require hundreds of different cultures.

In short, culture is great for targeted questions like pathogen detection. Shotgun metagenomics gives you the community-wide view — diversity and function in one test.

How many people are in the healthy comparison group?

The healthy comparison group currently includes 484 people. They were carefully screened against strict health criteria, which makes them a reliable benchmark for interpreting your patient's results.

What's the average number of species detected in the healthy comparison group?

On average, around 200 species are detected in healthy individuals. The 25th to 75th percentile range of the healthy comparison group sits between 170 and 230 species.

How many species can Microbiome Explorer identify within the Clostridium genus?

Our database can identify over 190 species of Clostridium. Of those, 75 species have been detected in the Microba Discovery Database.

Already have an account? Log in. Log in
New to Microba? Sign up today. Sign up to start referring

Sign up to our newsletter

Microbiome research, clinical insights, and product updates for healthcare practitioners, plus practical guidance for patients exploring their gut health.

    You don’t need to register for the newsletter as you are already on the list as a registered practitioner.